Uric Acid Crystals Meet White Blood Cells

This fascinating look at white blood cells in action against uric acid crystals goes a long way to explaining the agony of gout. The fragmentation of white blood cells as they fight urate crystals attracts more white blood cells to join the battle leading to a vicious circle of inflammation causing yet more inflammation.

The title, in layman’s terms, means “Looking at inflammation from uric acid crystals with large white blood cells”

Title:
Observations on phagocytosis of urate crystals by polymorphonuclear leucocytes.
Author:
Rajan KT.
Published:
Ann Rheum Dis. 1975 Feb;34(1):54-61.

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