[P Mb]

Hi Malik,

Thanks for responding. There are anecdotal reports of statins causing joint/muscle pain. So my theory is that since uric acid tends to agglomerate at injury sites it’s that’s that triggered my attacks.

It’s just a theory, though – the whole ‘metabolic syndrome’ thing is very difficult to pick your way through when you’re trying to focus on one element.

I’m afraid I’m taking my chances with the high cholesterol now and only taking the allopurinol – that may well be medically inadvisable, but it’s my choice.
We’re all different – and I do genuinely wish you well with your treatment(s).
If you can find the time sometime in future, it would be good to hear how your gout gets on with your statin therapy.

pb

[P Mb]

Hello Keith,

Thanks for your response. It’s a complicated area to be sure. I’ve been poking about in research papers too, but completely off the original thread subject now – mainly about uric acid in the body when you’re hyperuricemic but *don’t* have attacks.

It’s interesting yet scary the damage that UA can do (eg: to tendons). Needless to say I’m back on the 300mg allopurinol – despite the side effects!

What I’m interested in now are the chemical processes – eg: the *negative* effects of xanthine oxidase suppression; one thing is for sure though – biologically, none of these gout pathways are simple!

pb

[P Mb]

Hi Ucatsexas,

Good post.

I was diagnosed with (mild) SA too – and suffer with gout.
I am *convinced* there is a link there that needs investigation.
‘Better joints in the morning’ was the first thing I noted after going onto CPAP: it was a dead cert that I’d had a good night on the machine.

Were I a doctor I’d do a mandatory sleep study when anyone presented with gout – and probably one or two other chronic conditions too:

For ‘overweight people tend towards diabetes and gout’ read ‘overweight people tend to breathe less well at night, which encourages diabetes and gout’ – perhaps?

Could be a research project in there 🙂

pb

[P Mb]

Hello, ‘Nobody’ 🙂

My UA level was tested a few months ago and was ‘within expected parameters’. Though I have to say this wasn’t part of a testing programme, just a response to a flare. This is the NHS, after all… 😉 No diet changes to speak of either.

You’re probably right that this isn’t gout-related, though through grim experience I’ve found you pretty much have to treat every niggle as a potential attack trigger and jump on it immediately. Just a couple of Dicloflex can head off a painful six weeks! (Though I now have colchicine in my armoury – bit wary of taking it though – have probably read too many biochemistry sites…).

I’ll probably end up at the quacks one way or another – probably to beg for more anti-inflammatories!

Thanks for responding – I like the site.

pb

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