[charlie]

Thanks Guys for your informative replies.

I did not know about the continuing effect of Allopurinol and its half life and metabolism into Oxypurinol.That would suggest to me that the 14.9 reading could be disregarded as spurious. I did not have any signs of a new attack at that time. 

I will try reducing by maybe 150mg daily, wait a week and retest like I did before. I was surprised by the reading myself as I use a pill dispenser box so I rarely miss my dose. I was away for the weekend when I missed but it was only one day and I would have taken a half dose that evening as opposed to full dose in the morning. I am drinking about four pints of fluids daily (excluding wine or whiskey). I ate some prawns (I love seafood!) but doubt if food alone would account for that big a rise.

My basic aim is to titrate myself by adjusting my dose to get my UA level to 5 or 6 and try to maintain that with as low a dose as possible. I just hope I am out of the woods regarding attacks. I was close to giving up after about eight months of continous attacks in knees, feet and index finger. I read that only a small percentage of people who start Allo. contiunue taking it, and that of those who do continue only a small percentage are taking a dose high enough to lower their UA below 6. Maybe the 600mg daily was responsible for my eight months of agony….too much too soon.

I am considering trying the new drugs. Uloric, Febuxostat, Pegloticase are mentioned. Has anyone any feedback on these in use ? There is also a HIV drug that they have found dramatically lowers UA in the blood. It is RDEA594. This was an accidental find. Just shows that there are probably other drugs that would help gout sufferers but the fact we are a small minority means that drug companies have little interest in us. No new drugs in forty years says something.

Goutpal, Thanks for this site. It and other sites like it are a great source of comfort, information and inspiration to people with this affliction. 

Charlie

Since I posted this, I did another test. It came up “low” so that confirms that it is time to slowly reduce my Allopurinol. If the UA Sure is working accurately it is an indespensibly piece of equipment in the fight against gout.

[charlie]

I had terrible eczema too and its almost gone.

I am on Allopurinol for 9 months now.

Never thought it could be connected.

[Author]

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